It remains a prevalent global disease with two different treatment modalities of home-care desensitisation with the over-the-counter (OTC) desensitisers such as potassium, While 8% strontium acetate showed a greater clinical reduction in water jet stimulated DH on VAS than Pro-argin at all efficacy intervals, as demonstrated in Table 6. YYYY Colgate-Palmolive Company. Poster #3406, July 2018 IADR. J Evid Based Dent Pract. Lasting relief with 2x daily continued brushing. All rights reserved. YES Somewhat No Therefore, the first null hypothesis was that mean scores for pain due to DH among different treatment groups for immediate relief remain. Instant relief when applied directly to the sensitive tooth with the fingertip and gently massaged for 1 minute. Colgate-Palmolive Company 2018. *with direct application and daily brushing. Post-hoc analysis revealed a significant reduction in DH scores in treatment arms compared to control on completing the six-week trial (p<0.05). . ClinicalTrial.gov: National Library of Medicine (US). Was this answer helpful? Toothpaste doesn't only clean your teeth; we have products to help with a variety of tooth issues like sensitivity and more. Blocks the pain of sensitive teeth. Colgate uses need to categorize. Participantswere strictly advised to refrain from acidic food and drink intake at least four hours before following up visit. Grading of Recommendations, Assessment, Development and Evaluations. [33] again reported a 54% clinical reduction in DH with Pro-argin in eight weeks clinical trial using SCASS. Moreover, FCPS as a new bioactive material revealed promising potency of sustainable management of DH in a previously conducted trial by Ashwini et al. 2016;3(1):0504. 2017;2017:2. [32] reported statistically significant improvement in mechanical stimulated DH with Pro-argin immediately after topical application relative to 8% strontium Acetate in 2016. Colgate Sensitive Pro Relief was compared to a leading brand of desensitizing toothpaste containing stannous fluoride in a laboratory study, with confocal laser scanning microscopy and a novel imaging program used to qualify dentinal tubule occlusion. Colgate Sensitive Pro Relief Instant Relief, Plugging the channels that lead to sensitive tooth nerves to help relieve sensitivity. Ashwini S, Swatika K, Kamala DN. These then interact to form a complex with positive charge. Docimo et al. Based on the synthesis of study results, we can conclude that Pro-argin in Colgate Sensitive Pro-relief and 8% strontium acetate in Sensodyne Rapid Action both are effective for pain relief in one minute after application in DH with better immediate treatment response of Pro-argin than strontium acetate. 1997;24(11):80813. In comparison, the Pro-argin can make mechanical barrier of calcium phosphate precipitates on exposed dentinal tubules up to 2m depth by the interaction of positively charged arginine, amino acids and type 1 collagen fibres [8]. Colgate Sensitive Pro Relief Enamel Repair to strengthen weakened enamel and prevent enamel loss. 2008;29(8):1S-35S. This clinical trial has not included a run-in or washout period before the test phase due to time constraints and compliance of the potential participants. Apotekets varuid 29483 Varunummer 207000 Kategori Tandkrm, Ilningar i tnderna Varumrke For instant relief, just apply directly to the sensitive tooth with fingertip and gently massage for one minute. CONCLUSION: The study results support the following conclusions: (1) Colgate Sensitive Pro-Relief toothpaste provides a significantly more reduction in dentin hypersensitivity than Sensodyne. In addition, one-Way ANOVA with Post Hoc Tukey for pair-wise comparison was used to compare treatment groups computing percent change from baseline with formula (post-application mean scores-baseline mean scores/baseline mean scores). A total of 140 met the eligibility criteria with at least two sensitive teeth anterior to molars due to erosions or abrasions with or without an associated gingival recession. 29,95 kr. 1 Nathoo et al. These findings were similar to a previous study conducted by Schiff et al. The arginine, calcium carbonate and phosphate plug created by Colgate Sensitive Pro Relief remains intact with ongoing use, even when exposed to acid challenges. 2009; 20 (Spec Iss): 1722. Colgate Sensitive Pro-Relief efektywnie i szybko znosi nadwraliwo zbw, zamyka kanaliki zbinowe w ktrych s zakoczenia nerww, dziki czemu blokuje bl. Oral dentifrices have been marketed for pain relief within a minute for DH. Today's era of flourishing research in DH is based on incorporating bioactive ingredients in commercially available oral dentifrices that can induce deep intratubular remineralisation of dental hard tissues for permanent or long-term treatment purposes. It improves gum health and helps reduce factors that contribute to gum recession, a leading cause of tooth sensitivity. Sriranganathan D, Chen X, Hing KA, Kanwal N, Hill RG. Written informed consent was obtained with a signed agreement plan to visit for six weeks at interim efficacy intervals of day three, week two, week four, and week six. The dropouts of the participants at each efficacy interval may be considered the weakness of this trial that was due to COVID-19 lockdown. According to Holland's guidelines of conducting a trial for managing DH, two diagnostic tools are sufficient for quantitative assessment of the clinical efficacy of desensitisers. Dentifrices-containing Pro-argin showed a significant reduction in DH with mean scores of (4.201.70) followed by strontium acetate (4.651.87) followed by FCPS (5.101.88) one minute after application. J Dent Res. Click & Collect. da Cruz LPD, Hill RG, Chen X, Gillam DG. J Oral Rehabil. J Dent. Identifier NCT 04249336. In addition, they should be reproducible and clinically relevant to stimuli triggering pain in DH [35]. Pessoa, Loretto et al. By using this website, you agree to our Arshad, S., Zaidi, S.J.A. Provided by the Springer Nature SharedIt content-sharing initiative. Google Scholar. 3rd edition, Public Health England 2014. The sensitive toothpaste remineralises tooth enamel for more resistance against acid attacks. Colgate SENSITIVE INSTANT Relief Repair & Prevent Toothpaste for the daily oral care of patients with dentine hypersensitivity and gum problems. Post-application changes on SCASS were observed after one minute, three days, two, four, and six weeks, subsequently. . 2018;75:1221. Vu Pham T, Anh Nguyen T. Clinical evaluation of the desensitizing efficacy of a paste containing 8% arginine and calcium carbonate. California Privacy Statement, 2009;22(Spec No. Pro-Argin technology helps to seal and repair . For instant relief, just apply directly to the sensitive tooth with fingertip and gently massage for one minute. Moreover, there was no significant difference between dentifrices containing FCPS, Pro-argin, and 8% strontium acetate (p>0.05) on completion of trial after six weeks. With regular use, it creates a long-lasting protective barrier that acts as a seal against sensitivity. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Dentin hypersensitivity is characterized by a short, sharp pain arising from open dentin tubules in exposed dentin in response to external stimuli, which cannot be attributed to any other defect or disease. 3. 4.2 5 0 221 221 Colgate Sensitive Pro-Relief Enamel Rebuild toothpaste helps instantly repair sensitive teeth and provides lasting protection against hypersensitivity. A total of 128 participants completed the trial. The main etiological factors are abrasion and erosion that may or may not be associated with gingival recession in DH. The secondary objective of the study was to compare the clinical efficacy of Pro-argin, strontium acetate, and FCPS for immediate and sustained treatment response in DH that was measured on SCASS as a primary outcome measure and VAS as secondary outcome measure at efficacy intervals of one minute, day-three, week two, four and six. Effectiveness of dentifrices with new formulations for the treatment of dentin hypersensitivitya meta-analysis. Ingredients *Potassium Nitrate The Colgate Sensitive Pro Relief range features toothpastes that provide relief for sensitive teeth while addressing other common oral health concerns: Colgate Sensitive Pro Relief Repair and Prevent to protect against gingival recession. Indian J Dent Sci. Colgate Toothpaste relieves the discomfort of tooth irritation by still addressing the root causes. The burden of dentine hypersensitivity. 1):8A-15A. Results of our study, together with the results of the previous studies, confirm the immediate clinical efficacy of Pro-argin for the relief of DH. 2017;457:2530. The primary analysis population could be described as 32 participants per treatment group after lost to follow-ups of 12 out of 35 enrolled in the six-week trial who responded to the air blast stimulus for the primary outcome measure of treatment response one minute after topical application and after three days and two, four and six weeks subsequently, on SCASS with scores of2. It was measured by assaying change in SCASS scores of pains with Pro-argin and 8% strontium acetate after one minute of topical application on the sensitive teeth. 1). For children 6-12 years of age, once a week or less frequently. was used for statistical analysis. Product Details Page . The price for Colgate Sensitive Pro-Relief is set at RM12.80 to avoid being categorized at RM13.00. 2019;40(10):6537 (quiz 8). Modified bass brushing method was demonstrated on the same model before the first application of dentifrices in the dental clinic. In vitro analysis suggested that FCPS-based dentifrice enabled the slow and sustained release of fluoride contents, resulting in more stable fluorapatite crystals in saliva [14, 15]. For patients in the dental chair, it can be used to rapidly ease hypersensitivity pain, facilitate examinations and make dental procedures more comfortable. [10] examined the evidence for strontium acetate and Pro-argin in 2018, and their findings depicted low quality of evidence for strontium acetate on the Grading of Recommendations, Assessment, Development, and Evaluations system (GRADE). observed a significantly greater reduction in sensitivity from air and tactile stimuli when compared to a potassium ion toothpaste, an effect sustained at two, four and eight weeks of use. A head-to-head comparative evaluation of these most effective bioactive agents, such as arginine and BAG-based desensitisers, was suggested by Martins et al. Gentle whitening formula. Hu M-L, Zheng G, Zhang Y-D, Yan X, Li X-C, Lin H. Effect of desensitizing toothpastes on dentine hypersensitivity: a systematic review and meta-analysis. 2013;41:S317. Colgate Sensitive Pro-Relief Enamel Rebuild also: Fights cavities Strengthens enamel Freshens breath Vegan . blokerer jeblikkeligt smerter fra isninger. OTC dentifrices with Pro-argin and strontium acetate are effective for immediate pain relief from DH, and FCPS could be the best possible treatment option for long term management of DH. Bakri MM, Hossain MZ, Razak FA, Saqina ZH, Misroni AA, Ab-Murat N, et al. Clin Cosmet Investig Dent. 2016;8:114. 2010;23(Spec No A):14A-9A. in 2019 using BioMin F and Pro-argin. [28] reporting the immediate effect of 8% strontium acetate in alleviating clinical symptoms of DH with clinically and statistically significant (<0.001) measures relative to baseline [26]. A toothbrushing demonstration model from Nissin Company specification [PE-ORT002] was used to explain to the study participants about applying OTC dentifrices for one minute with the participant's finger. J Clin Dent. Thus, 128 participants completed the trial and were statistically analyzed for primary outcome measure of SCASS scores after lost to follow up (Fig. Directions for Use: For instant relief, apply directly to the sensitive tooth with finger tip and massage gently for 1 minute, up to twice a day and for children 6-12 years once a week or less frequently. Dentinal tubules occluded by bioactive glass-containing toothpaste exhibit high resistance toward acidic soft drink challenge. Colgate Sensitive Pro-Relief Complete Protection sensitivity toothpaste is clinically proven for instant and lasting relief from sensitivity pain. Thank you for your feedback. Table 2 presents descriptive statistics of the primary analysis population as the primary statistical analysis was performed for 47 males and 81 females of age ranging from 18 to 50years with a mean age of 34.18.9. Nathoo S, Delgado E, Zhang YP, DeVizio W, Cummins D, Mateo LR: Comparing the efficacy in providing instant relief of dentine hypersensitivity of a new toothpaste containing 8.0% arginine, calcium carbonate, and 1450 ppm fluoride to a benchmark desensitizing toothpaste containing 2% potassium ion and 1450 ppm fluoride and to a control toothpaste with 1450 ppm fluoride: A three-day clinical study in New Jersey, USA. Panagakos F, Schiff T, Guignon A. Dentin hypersensitivity: effective treatment with an in-office desensitizing paste containing 8% arginine and calcium carbonate. Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. compared the Pro-Argin formulation with a calcium sodium phosphosilicate toothpaste, demonstrating 88% versus 50% occlusion respectively. Exclusive Pro-Argin formula. 2013;41(2):18794. I am interested to hear you guys opinion and thought about it. Most sensitive toothpastes primarily numb the discomfort, whereas Colgate Sensitive Pro-Relief works to relieve sensitivity by plugging the channels that lead to sensitive tooth nerves. 2019;81:16. 1. 3Intervention for Group C denotes Sensodyne Rapid Action. When you recommend Colgate Sensitive Pro Relief, you can help your dentin hypersensitivity patients to enjoy a pain-free life, confident in the knowledge that youre providing a highly effective, evidence-based solution. (Table 1) (Fig. and Ayad et al. TVC Category: Colgate Tooth Paste Benefits Clinically proven sensitivity relief. Tel: +381 (0)21 452-910, +381 (0)21 420-758. https://doi.org/10.17352/2394-8418.00003. Docimo R et al. When it begins to interfere with oral hygiene, it can also lead to poor oral health outcomes. Help Caregivers Understand Caries | Colgate Professional, compared to a leading brand of desensitizing toothpaste, Colgate Sensitive Pro Relief Repair and Prevent, Colgate Sensitive Pro Relief Enamel Repair, Colgate Sensitive Pro Relief Multi Protection. Providing effective solutions for this prevalent condition is a priority for every dental professional, and Colgates Pro-Argin technology is helping dentists lead the way. Colgate* Sensitive Pro-Relief TM/MC Toothpaste with Pro-Argin TM/MC Technology is the first toothpaste that is clinically proven to provide instant & lasting relief from dentin hypersensitivity. Explore the videos and articles found on this page to assist in better oral care. Frequency of dentin hypersensitivity: a cross-sectional study. Clinically proven lasting relief for 8 weeks. Schiff T, Delgado E, Zhang Y, Cummins D, DeVizio W, Mateo L. Clinical evaluation of the efficacy of an in-office desensitizing paste containing 8% arginine and calcium carbonate in providing instant and lasting relief of dentin hypersensitivity. 2010;11:32. Pro-Argin showed a greater reduction in DH with mean scores of (1.340.68) (4.201.70) (3.052.17) followed by strontium acetate (1.570.81) (4.651.87) (3.751.97) on SCASS and VAS for mechanical and water jet stimuli, one minute after application. With regular use, it reduces teeth sensitivity and helps to strengthen gums and prevent gum recession. Pro-Argin technology provides instant* and long-lasting, Oral Care Products | Colgate Professional. The statistician was also kept blinded. We were using the PAS version.11, two independent sample t-test with 95% confidence interval and 80% power of test, meanSD of air blast stimulus test score of test group 1.860.41 and control group 2.220.41 two weeks after baseline test score, the calculated sample size was 22 [21] which was raised to 35 including five as drop out for each group (Fig. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. This toothpaste really does not help at all with symptoms of sensitive teeth. ^Vs novamin/sodium fluoride technology and stannous fluoride/sodium fluoride technology (p<0.05). J Clin Dent. J Dent Probl Solut. In this way, variability in individuals' pain response was tried to be controlled and will be discussed in part 2 of this manuscript. Sealed channels protect against pain caused by hot, cold and sweet stimuli. Aust Dent J. Colgate Sensitive Pro-Relief (Toothpaste): 1.9 out of 5 stars from 91 genuine reviews on Australia's largest opinion site ProductReview.com.au. 2 Docimo et al. Colgate Sensitive Pro-Relief works by plugging the channels to block tooth sensitivity and with regular use, it builds a long-lasting protective barrier that acts like a seal against sensitivity. Felix J, Ouanounou A. Dentin hypersensitivity: etiology, diagnosis, and management. These findings were similar to a previous study conducted by Schiff et al. The first post-treatment measure of SCASS and VAS scores was obtained immediately after removing dentifrices from teeth. We provided oral hygiene instructions and ways of relieving their pain from DH to improve their quality of life. Purchased in August 2019 at Coles for $5. YYYY Colgate-Palmolive Company. This toothpaste contains a unique formula that blocks the pathways to pain instantly Its clinically proven formula provides INSTANT RELIEF from the first usage, LONG-LASTING RELIEF with twice everyday use. Google Scholar. J Clin Periodontol. Pro-Argin technology is occlusive. YYYY Colgate-Palmolive Company. Colgate-Palmolive Company 2018. The comparative evaluation was done for the clinical efficacy of Pro-argin and 8% strontium acetate, and a statistically significant (p>0.05) difference was not found between these two formulations in the current study. J Clin Dent 20 (2009), special issue 17-22, 3. These ingredients resulted in rapid fluorapatite crystallisation at exposed tubular ends of dentin [12]. Desensitizing toothpastes for dentin hypersensitivity: a network meta-analysis. Saba Arshad. A meta-analysis by Yang et al. A randomised controlled, triple-blinded, phase-3 clinical trial was conducted at the Department of Periodontology at Dr Ishrat-ul-Ebad Khan Institute of Oral Health Sciences (DIKIOHS) in Dow University of Health Sciences (DUHS), Karachi, Pakistan from September 2019 to December 2020. Colgate Sensitive Pro-Relief It works by plugging the channels to block tooth sensitivity and with regular use. 2018;9(3):3306. J Dent. 2018;2018:110. Colgate Sensitive Plus Toothpaste developed for sensitive teeth provides sensitivity protection And helps in Enamel Repair, Cavity . J Oral Sci. Benefits. No side effects, apart from money not well spent. 2017;71:18. However, there was no significant treatment difference between dentifrices containing Pro-argin and strontium acetate (p>0.05) at each efficacy interval. Colgate Sensitive Pro-Relief Enamel Repair Toothpaste provides clinically proven instant and lasting relief for sensitive teeth For instant relief, apply directly to each sensitive tooth with finger tip and gently massage for 1 minute, up to twice daily Colgate Sensitive Pro Relief offers a solution that is clinically proven to relieve sensitivity pain. 90 sold. 1Intervention for Group A denotes BioMin F. 2Intervention for Group B denotes Colgate Sensitive Pro relief. 2015;28(1):404. 1). In addition, the frequency of participants diagnosed with DH using air blast stimulus was observed as 36.8% at the time of enrolment in the six-week clinical trial that was found consistent with findings of a survey report demonstrating 36.4% frequency of DH among adults in Karachi, Pakistan [24]. CONSORT flow chart. Oral dentifrices were provided to the subject free of cost. https://doi.org/10.1186/s12903-021-01864-x, DOI: https://doi.org/10.1186/s12903-021-01864-x. Holland GR, Narhi MN, Addy M, Gangarosa L, Orchardson R. Guidelines for the design and conduct of clinical trials on dentine hypersensitivity. Shrimathi S. Effect of BiominF, NovaminR, Argin and nanohydroxy particles containing dentifrices on dentine hypersensitivity and gingivitis among 3544 years aged population of Madurai district: a randomized controlled trial (RCT). Colgate SENSITIVE INSTANT Relief Repair & Prevent toothpaste with PRO-ARGIN Technology and Zinc provides clinically proven instant* and lasting sensitivity relief1-2 plus lasting gum protection3. Oral Care Products | Colgate Professional, Colgate Toothpaste - Dentists & Patients | Colgate Professional, Colgate SENSITIVE INSTANT Relief Repair & Prevent Toothpaste, Instantly* relieves dentine hypersensitivity, Long-lasting relief from the pain of sensitive teeth, Helps strengthen gums and prevent gum recession, Recommended fluoride level for caries protection (1450ppm). Cite this article. How does Colgate Sensitive Pro-Relief Repair & Prevent work? The authors declare that they have no competing interests (financial and non-financial) related to the article. Significantly greater sensitivity reduction with twice - daily brushing compared to control toothpaste with potassium ions. Friedman Test was used to observe post-application change in treatment responses within the group for 6weeks. [22] reporting the instant relief from DH by 44.1% with Pro-argin on SCASS. Mode of action studies on a new desensitizing dentifrice containing 8.0% arginine, a high cleaning calcium carbonate system and 1450 ppm fluoride. Compend Contin Educ Dent. Helps restore natural whiteness of teeth. Naturally, the researchers wondered whether it could help shield a person from acquiring the virus.
